Theodore J Kottom Selected Research

Pneumocystis Pneumonia (Pneumocystis carinii Pneumonia)

6/2022	Preclinical and Toxicology Studies of BRD5529, a Selective Inhibitor of CARD9.
12/2021	Additional C-type lectin receptors mediate interactions with Pneumocystis organisms and major surface glycoprotein.
5/2021	Survey of the Transcription Factor Responses of Mouse Lung Alveolar Macrophages to Pneumocystis murina.
1/2021	Current State of Carbohydrate Recognition and C-Type Lectin Receptors in Pneumocystis Innate Immunity.
10/2020	A critical role for CARD9 in pneumocystis pneumonia host defence.
1/2018	Dectin-2 Is a C-Type Lectin Receptor that Recognizes Pneumocystis and Participates in Innate Immune Responses.
2/2017	Characterization of N-Acetylglucosamine Biosynthesis in Pneumocystis species. A New Potential Target for Therapy.
8/2012	Chitinases in Pneumocystis carinii pneumonia.
7/2006	Pneumocystis cell wall beta-glucans induce dendritic cell costimulatory molecule expression and inflammatory activation through a Fas-Fas ligand mechanism.
6/2005	Pneumocystis cell wall beta-glucans stimulate alveolar epithelial cell chemokine generation through nuclear factor-kappaB-dependent mechanisms.

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Theodore J Kottom Research Topics

Disease

10	Pneumocystis Pneumonia (Pneumocystis carinii Pneumonia) 06/2022 - 06/2005
8	Infections 12/2021 - 01/2003
4	Pneumonia (Pneumonitis) 01/2017 - 01/2003
2	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2021 - 01/2020
2	Cysts 02/2016 - 08/2010
2	Inflammation (Inflammations) 07/2015 - 06/2005
1	Mycoses (Diseases, Fungus) 06/2022
1	Weight Gain 06/2022
1	Fibrosis (Cirrhosis) 12/2021
1	Porcine Reproductive and Respiratory Syndrome (PRRS) 01/2021
1	Lung Injury 10/2020
1	Pneumocystis Infections 10/2020
1	Starvation 01/2020
1	Chronic Obstructive Pulmonary Disease (COPD) 04/2010
1	B-Cell Lymphoma (Lymphoma, B Cell) 04/2010
1	Leukemia 04/2010

Drug/Important Bio-Agent (IBA)

6	GlucansIBA 06/2022 - 01/2003
6	CytokinesIBA 01/2021 - 01/2003
5	Proteins (Proteins, Gene)FDA Link 06/2022 - 04/2010
3	Messenger RNA (mRNA)IBA 12/2021 - 04/2010
3	beta-GlucansIBA 08/2010 - 01/2003
2	Bleomycin (Blenoxane)FDA LinkGeneric 12/2021 - 01/2020
2	C-Type Lectins (C-Type Lectin)IBA 12/2021 - 01/2017
2	ChemokinesIBA 01/2021 - 01/2003
2	EnzymesIBA 01/2020 - 08/2010
2	Fibronectins (Fibronectin)IBA 02/2008 - 11/2003
1	BRD5529IBA 06/2022
1	Interleukin-6 (Interleukin 6)IBA 06/2022
1	Pharmaceutical PreparationsIBA 06/2022
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2022
1	indium-bleomycinIBA 12/2021
1	nintedanibIBA 12/2021
1	Vardenafil Dihydrochloride (Levitra)FDA Link 12/2021
1	Galactose (Galactopyranose)FDA LinkGeneric 12/2021
1	Glycoproteins (Glycoprotein)IBA 12/2021
1	AcetylgalactosamineIBA 12/2021
1	Transcription Factors (Transcription Factor)IBA 05/2021
1	Membrane Glycoproteins (Membrane Glycoprotein)IBA 01/2021
1	Pattern Recognition ReceptorsIBA 01/2021
1	Sodium Glutamate (Accent)IBA 01/2021
1	Metalloproteases (Metalloproteinases)IBA 01/2021
1	SugarsIBA 01/2020
1	CB-839IBA 01/2020
1	Adenosine Triphosphate (ATP)IBA 01/2020
1	GlutaminaseIBA 01/2020
1	Glutamine (L-Glutamine)FDA Link 01/2020
1	NucleotidesIBA 01/2020
1	Phosphates (Orthophosphate)IBA 01/2020
1	mouse dectin-2IBA 01/2018
1	nikkomycinIBA 02/2017
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2017
1	ChitinasesIBA 08/2012
1	GlycosphingolipidsIBA 07/2012
1	SmokeIBA 04/2010
1	LigandsIBA 04/2010
1	IntegrinsIBA 02/2008
1	NF-kappa B (NF-kB)IBA 06/2005
1	VitronectinIBA 11/2003

Therapy/Procedure

1	Therapeutics 05/2021